Directory of PET Center in North America

Editors: H. Donald Burns, Terence G. Hamill,
Raymond E. Gibson, Timothy J. McCarthy,
Robert F. Dannals, and Richard Frank

Table of Contents

University of California, Berkeley, CA
University of California, Irvine, CA
University of Southern California, Los Angeles, CA
University of California, Los Angeles, CA
West LA VA PET Center, Los Angeles, CA
VA Palo Alto Health Care System, Palo Alto, CA
CA Affairs Medical Ctr/UCSD, San Diego, CA
Emory Univesity, Atlanta, GA
Indiana University, Indianapolis, IN
University of Iowa, Iowa City, IA
University of Kansas, Kansas City, KS
Biomedical Research Foundation, Shreveport, LA
Massachusetts General Hospital, Boston, MA
Johns Hopkins University, Baltimore, MD
National Institute on Drug Abuse, Baltimore, MD
National Institutes of Health, Bethesda, MD
The University of Michigan, Ann Arbor, MI
Wayne State University, Detroit, MI
Minneapolis VA PET Center, Minnaeapolis, MN
Mayo Clinic, Rochester, MN
Washington University, ST. Louis, MO
Duke University, Durhma, NC
Wake Forest University, Winston-Salem, NC
Alegent Health Bergan Mercy PET Ctr, Omaha, NE
Brookhaven National Laboratory, Upton, NY
State University of New York, Buffalo, NY
Dent PET Center, Buffalo, NY

Columbia University, New York, NY
Mount Sinai School of Medicine, New York, NY
North Shore University Hospital, Manhasset, NY
The Cleveland Clinic, Cleveland, OH
Case Western Reserve University, Cleveland, OH
Kettering Memorial Hospital, Dayton, OH
University of Pennsylvania, Philadelphia, PA
The University of Pittsburgh Medical Center, Pittsburgh, PA
Vanderbilt University, Nashville, TN
North Texas Clinical PET Institute, Dallas, TX
The University of Texas Medical School, Houston, TX
University of Texas Health Science Center, San Antonio, TX
Metro Region PET Center, Annandale, VA
The University of Washington, Seattle, WA
University of Wisconsin, Madison, MI
West Virginia University, Morgantown, WV
McMaster University Medical Center, Hamilton, Ontario
The Montreal Neurological Institute, Montreal, Quebec
Sherbrooke University Hospital, Sherbrooke, Quebec
The University of Toronto, Toronto, Ontario
The University of British Columbia, Vancouver, British Columbia

Conduct periodic, topical workshops to address specific, relevant issues.

Publish semi-annual newsletter containing:

1) abstracts of relevant publications
2) calendar of related scientific meetings
3) news concerning drug research, development or regulatory issues
4) commentary by SNIDD members or invited experts.

Hold biennial symposium or workshop on the use of imaging in drug research and development.

Sponsor presentations at related national and international scientific meetings.

Publish educational material related to the use of imaging in drug research and develpment.

The Society of Non-Invasive Imaging in Drug Development (SNIDD) is an Institute of the Academy of Molecular Imaging. SNIDD is an all volunteer, educational organization which has the goal of increasing the appropriate use of non-invasive, imaging technology as tools in drug research and development.

We provide opportunities for scientists from the drug industry and from academic research centers to learn more about the potential of non-invasive imaging technology for providing valuable information that can increase the efficiency of new pharmaceutical research and development.

Our overall view is that non-invasive imaging techniques are powerful research tools for scientists involved in drug discovery, research and development. Over the past 10 years, the use of imaging in drug research has gradually increased. We hope, by the efforts of SNIDD and similar organizations, that this technology will become more widely used since it has the potential of increasing the efficiency of drug discovery and development programs by reducing both the overall time required and the cost of these programs.

We expect to particpate in conferences organized by AMI, and sponsor independent symposia on this subject, publish a biannual newsletter and continue to provide support for presentations at appropriate national and international meetings.

Non-invasive imaging techniques can be used to obtain information on in vivo biochemistry and physiology in experimental animals and man that cannot be obtained in any other way. As applied to drug discovery and development, information obtainable via imaging can be divided into four categories: 1) determination of desirable, pharmacological effects or undesirable side effects (i.e., the effect of the drug candidate on in vivo biochemistry and physiology); 2) the interaction of a drug or drug candidate with the desired target (e.g., receptor, enzyme or transport system), including dose occupancy relationships and kinetic information; 3) the delivery of a drug to a specific target; and 4) the absorption, distribution, metabolism and elimination of the labeled drug candidate.

SPECT: Single Photon Emission Computed Tomography

PET: Positron Emission Tomography

MRI: Magnetic Resonance Imaging

CT: Computed Tomography

US: Ultrasound